Serotonin Modulator (Antidepressant / Sleep Aid)Disqualifying

Trazodone

Brand names: Desyrel|Last verified: 2026-03-01

FAA Pathway: Do Not Issue (DNI) list

Trazodone is on the FAA's DNI list. Whether prescribed for depression or insomnia, it is disqualifying due to its sedating effects. It is not one of the four approved SSRIs.

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Always report all medications on your FAA medical application (Form 8500-8, Item 17a), even OTC medications. Failure to disclose is a far bigger issue than the medication itself.

Certification Details

FAA Status
Do Not Issue (DNI) list
Sedation
Significant sedating effects — often used as sleep aid
Not an Approved SSRI
Does not qualify under SSRI protocol
Certificate Classes
All classes affected

Sources

  • FAA Do Not Issue Table

Last verified: 2026-03-01

Frequently Asked Questions

Is Trazodone allowed for pilots?

The FAA considers Trazodone (Desyrel) to be "Disqualifying" for medical certification purposes. Trazodone is on the FAA's DNI list. Whether prescribed for depression or insomnia, it is disqualifying due to its sedating effects. It is not one of the four approved SSRIs.

What is the FAA status of Trazodone?

Trazodone has a status of "Disqualifying" under FAA medical certification policy. The certification pathway is: Do Not Issue (DNI) list.

Can I fly while taking Trazodone?

Trazodone is currently disqualifying for FAA medical certification. You cannot fly while taking this medication. A washout period and evaluation are typically required after discontinuation. Consult an AME or aviation attorney before making any medication changes.

Important Notice

The FAA does not publish a comprehensive list of “approved” medications. The information on this page represents our interpretation of publicly available FAA guidance and is provided for informational and educational purposes only. It does not constitute medical advice, legal advice, or a guarantee of certification outcome.

The primary issue with the FAA is always whether the underlying medical condition — not just the medication — is compatible with safe flight. You should only start, stop, or change medications after consulting your treating physician. Always consult with a qualified Aviation Medical Examiner (AME) for guidance specific to your situation. FAA policies are subject to change. ClearedMed is not affiliated with or endorsed by the FAA.