Risankizumab
Brand names: Skyrizi|Last verified: 2026-09-12
FAA Pathway: Acceptable if the underlying condition qualifies — 2-week ground trial, 4-hour no-fly after each dose
The FAA lists risankizumab (Skyrizi) as an acceptable medication when used alone, as long as the underlying condition qualifies for certification — your diagnosis is what determines eligibility. You must complete a 2-week ground trial when starting and not fly for 4 hours after each dose. FDA-approved biosimilars are also acceptable, and switching between biologics for the same condition requires a 48-hour ground trial.
Related Resources
Pilot Tip
Always report all medications on your FAA medical application (Form 8500-8, Item 17a), even OTC medications. Failure to disclose is a far bigger issue than the medication itself.
Certification Details
Sources
- FAA AME Guide — Pharmaceuticals: Biologics, Biosimilars, Non-Biologics (faa.gov/ame_guide/media/Biologics_Biosimilars_Non-Biologics.pdf)
Last verified: 2026-09-12
Frequently Asked Questions
Is Risankizumab allowed for pilots?
The FAA considers Risankizumab (Skyrizi) to be "Conditionally Approved" for medical certification purposes. The FAA lists risankizumab (Skyrizi) as an acceptable medication when used alone, as long as the underlying condition qualifies for certification — your diagnosis is what determines eligibility. You must complete a 2-week ground trial when starting and not fly for 4 hours after each dose. FDA-approved biosimilars are also acceptable, and switching between biologics for the same condition requires a 48-hour ground trial.
What is the FAA status of Risankizumab?
Risankizumab has a status of "Conditionally Approved" under FAA medical certification policy. The certification pathway is: Acceptable if the underlying condition qualifies — 2-week ground trial, 4-hour no-fly after each dose.
Can I fly while taking Risankizumab?
Flying while taking Risankizumab may be possible through the FAA's Special Issuance process. You will need to meet specific requirements and obtain approval before exercising pilot privileges. Consult an experienced AME for guidance.
Important Notice
The FAA does not publish a comprehensive list of “approved” medications. The information on this page represents our interpretation of publicly available FAA guidance and is provided for informational and educational purposes only. It does not constitute medical advice, legal advice, or a guarantee of certification outcome.
The primary issue with the FAA is always whether the underlying medical condition — not just the medication — is compatible with safe flight. You should only start, stop, or change medications after consulting your treating physician. Always consult with a qualified Aviation Medical Examiner (AME) for guidance specific to your situation. FAA policies are subject to change. ClearedMed is not affiliated with or endorsed by the FAA.