Lamotrigine
Brand names: Lamictal|Last verified: 2026-03-01
FAA Pathway: Special Issuance — depends on indication
Lamotrigine may be conditionally approved depending on the indication. If used for seizures, the seizure disorder itself is typically disqualifying. If used as a mood stabilizer for bipolar disorder, that condition is also disqualifying. Some off-label uses may have a pathway through Special Issuance.
Related Resources
Pilot Tip
Always report all medications on your FAA medical application (Form 8500-8, Item 17a), even OTC medications. Failure to disclose is a far bigger issue than the medication itself.
Certification Details
Sources
- FAA AME Guide, Neurology / Psychiatry
Last verified: 2026-03-01
Frequently Asked Questions
Is Lamotrigine allowed for pilots?
The FAA considers Lamotrigine (Lamictal) to be "Conditionally Approved" for medical certification purposes. Lamotrigine may be conditionally approved depending on the indication. If used for seizures, the seizure disorder itself is typically disqualifying. If used as a mood stabilizer for bipolar disorder, that condition is also disqualifying. Some off-label uses may have a pathway through Special Issuance.
What is the FAA status of Lamotrigine?
Lamotrigine has a status of "Conditionally Approved" under FAA medical certification policy. The certification pathway is: Special Issuance — depends on indication.
Can I fly while taking Lamotrigine?
Flying while taking Lamotrigine may be possible through the FAA's Special Issuance process. You will need to meet specific requirements and obtain approval before exercising pilot privileges. Consult an experienced AME for guidance.
Important Notice
The FAA does not publish a comprehensive list of “approved” medications. The information on this page represents our interpretation of publicly available FAA guidance and is provided for informational and educational purposes only. It does not constitute medical advice, legal advice, or a guarantee of certification outcome.
The primary issue with the FAA is always whether the underlying medical condition — not just the medication — is compatible with safe flight. You should only start, stop, or change medications after consulting your treating physician. Always consult with a qualified Aviation Medical Examiner (AME) for guidance specific to your situation. FAA policies are subject to change. ClearedMed is not affiliated with or endorsed by the FAA.