Opioid Analgesic (Pain — Patch/Transmucosal)Disqualifying

Fentanyl

Brand names: Duragesic, Actiq, Subsys|Last verified: 2026-09-12

FAA Pathway: Do Not Issue for chronic use (controlled substance); Do Not Fly for any use

Fentanyl (patches, lozenges, and other forms) is a potent narcotic and a controlled substance. Patches and other long-acting forms are used for ongoing pain, and the FAA's Do Not Issue table covers any ongoing prescription for chronic use of a controlled substance. Narcotic pain relievers are also on the Do Not Fly table, so do not fly while using fentanyl or until the no-fly time has passed after your last dose. The underlying pain condition is evaluated separately.

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Medication Checker

Related Resources

Pilot Tip

Always report all medications on your FAA medical application (Form 8500-8, Item 17a), even OTC medications. Failure to disclose is a far bigger issue than the medication itself.

Certification Details

FAA Status

Do Not Issue for chronic use — controlled substance (FAA DNI/DNF table)

Short-Term Use

Do Not Fly — no flying during use or until at least 5 times the maximum half-life after the last dose

Patches

Drug levels can persist after a patch is removed — confirm the wait with your AME

Underlying Condition

The painful condition is evaluated separately

Certificate Classes

All classes affected

Sources

FAA Do Not Issue Table
FAA Do-Not-Issue/Do-Not-Fly Table (faa.gov/ame_guide/media/DNI_DNF_tables.pdf)
FAA AME Guide — Pharmaceuticals: Controlled Substances and CBD (faa.gov/ame_guide/media/Controlled_Substances_and_CBD_Products.pdf)

Last verified: 2026-09-12

Frequently Asked Questions

Is Fentanyl allowed for pilots?

The FAA considers Fentanyl (Duragesic, Actiq, Subsys) to be "Disqualifying" for medical certification purposes. Fentanyl (patches, lozenges, and other forms) is a potent narcotic and a controlled substance. Patches and other long-acting forms are used for ongoing pain, and the FAA's Do Not Issue table covers any ongoing prescription for chronic use of a controlled substance. Narcotic pain relievers are also on the Do Not Fly table, so do not fly while using fentanyl or until the no-fly time has passed after your last dose. The underlying pain condition is evaluated separately.

What is the FAA status of Fentanyl?

Fentanyl has a status of "Disqualifying" under FAA medical certification policy. The certification pathway is: Do Not Issue for chronic use (controlled substance); Do Not Fly for any use.

Can I fly while taking Fentanyl?

Fentanyl is currently disqualifying for FAA medical certification. You cannot fly while taking this medication. A washout period and evaluation are typically required after discontinuation. Consult an AME or aviation attorney before making any medication changes.

Important Notice

The FAA does not publish a comprehensive list of “approved” medications. The information on this page represents our interpretation of publicly available FAA guidance and is provided for informational and educational purposes only. It does not constitute medical advice, legal advice, or a guarantee of certification outcome.

The primary issue with the FAA is always whether the underlying medical condition — not just the medication — is compatible with safe flight. You should only start, stop, or change medications after consulting your treating physician. Always consult with a qualified Aviation Medical Examiner (AME) for guidance specific to your situation. FAA policies are subject to change. ClearedMed is not affiliated with or endorsed by the FAA.