Antiplatelet AgentGenerally Approved

Clopidogrel

Brand names: Plavix|Last verified: 2026-03-01

FAA Pathway: Standard issuance; underlying cardiac condition evaluated separately

Clopidogrel is not on the FAA DNI list and is generally acceptable. However, the underlying condition requiring antiplatelet therapy (coronary stent, stroke prevention) typically requires Special Issuance evaluation.

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Related Resources

Pilot Tip

Always report all medications on your FAA medical application (Form 8500-8, Item 17a), even OTC medications. Failure to disclose is a far bigger issue than the medication itself.

Certification Details

Key Requirements

Underlying cardiac condition must be certifiable

Certificate Classes

Depends on underlying condition

Notes

Medication itself acceptable; condition drives pathway

Monitoring

Per cardiologist and FAA requirements for underlying condition

Sources

FAA AME Guide, Pharmaceuticals

Last verified: 2026-03-01

Frequently Asked Questions

Is Clopidogrel allowed for pilots?

The FAA considers Clopidogrel (Plavix) to be "Generally Approved" for medical certification purposes. Clopidogrel is not on the FAA DNI list and is generally acceptable. However, the underlying condition requiring antiplatelet therapy (coronary stent, stroke prevention) typically requires Special Issuance evaluation.

What is the FAA status of Clopidogrel?

Clopidogrel has a status of "Generally Approved" under FAA medical certification policy. The certification pathway is: Standard issuance; underlying cardiac condition evaluated separately.

Can I fly while taking Clopidogrel?

Clopidogrel is generally compatible with flying. However, you must report it on your FAA medical application (Form 8500-8) and ensure you are not experiencing side effects that could impair flight safety. Always consult your Aviation Medical Examiner (AME).

Important Notice

The FAA does not publish a comprehensive list of “approved” medications. The information on this page represents our interpretation of publicly available FAA guidance and is provided for informational and educational purposes only. It does not constitute medical advice, legal advice, or a guarantee of certification outcome.

The primary issue with the FAA is always whether the underlying medical condition — not just the medication — is compatible with safe flight. You should only start, stop, or change medications after consulting your treating physician. Always consult with a qualified Aviation Medical Examiner (AME) for guidance specific to your situation. FAA policies are subject to change. ClearedMed is not affiliated with or endorsed by the FAA.