Tricyclic AntidepressantDisqualifying

Amitriptyline

Brand names: Elavil|Last verified: 2026-03-01

FAA Pathway: Do Not Issue (DNI) list

Amitriptyline is on the FAA's DNI list. All tricyclic antidepressants are disqualifying due to their sedating, anticholinergic, and cardiac effects. Even low doses for migraine or neuropathy are disqualifying.

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Pilot Tip

Always report all medications on your FAA medical application (Form 8500-8, Item 17a), even OTC medications. Failure to disclose is a far bigger issue than the medication itself.

Certification Details

FAA Status

Do Not Issue (DNI) list — all tricyclics

Off-Label Use

Even for migraine or neuropathy, still disqualifying

Certificate Classes

All classes affected

Notes

Significant cardiac effects including QT prolongation

Sources

FAA Do Not Issue Table

Last verified: 2026-03-01

Frequently Asked Questions

Is Amitriptyline allowed for pilots?

The FAA considers Amitriptyline (Elavil) to be "Disqualifying" for medical certification purposes. Amitriptyline is on the FAA's DNI list. All tricyclic antidepressants are disqualifying due to their sedating, anticholinergic, and cardiac effects. Even low doses for migraine or neuropathy are disqualifying.

What is the FAA status of Amitriptyline?

Amitriptyline has a status of "Disqualifying" under FAA medical certification policy. The certification pathway is: Do Not Issue (DNI) list.

Can I fly while taking Amitriptyline?

Amitriptyline is currently disqualifying for FAA medical certification. You cannot fly while taking this medication. A washout period and evaluation are typically required after discontinuation. Consult an AME or aviation attorney before making any medication changes.

Important Notice

The FAA does not publish a comprehensive list of “approved” medications. The information on this page represents our interpretation of publicly available FAA guidance and is provided for informational and educational purposes only. It does not constitute medical advice, legal advice, or a guarantee of certification outcome.

The primary issue with the FAA is always whether the underlying medical condition — not just the medication — is compatible with safe flight. You should only start, stop, or change medications after consulting your treating physician. Always consult with a qualified Aviation Medical Examiner (AME) for guidance specific to your situation. FAA policies are subject to change. ClearedMed is not affiliated with or endorsed by the FAA.