Benzodiazepine (Anti-Anxiety)Disqualifying

Alprazolam

Brand names: Xanax|Last verified: 2026-03-01

FAA Pathway: Do Not Issue (DNI) list

Alprazolam and all benzodiazepines are on the FAA's Do Not Issue list. These medications are disqualifying due to their sedating effects and potential for dependence. A significant washout period is required after discontinuation.

Check your medications

Look up any medication in our FAA compatibility database.

Medication Checker

Related Resources

Pilot Tip

Always report all medications on your FAA medical application (Form 8500-8, Item 17a), even OTC medications. Failure to disclose is a far bigger issue than the medication itself.

Certification Details

FAA Status

Do Not Issue (DNI) list — all benzodiazepines

Washout Period

Varies; typically requires substance abuse evaluation

Underlying Condition

Anxiety disorder itself requires separate FAA evaluation

Certificate Classes

All classes affected

Next Steps

Consult AOPA or an AME experienced with anxiety cases

Sources

FAA Do Not Issue Table

Last verified: 2026-03-01

Frequently Asked Questions

Is Alprazolam allowed for pilots?

The FAA considers Alprazolam (Xanax) to be "Disqualifying" for medical certification purposes. Alprazolam and all benzodiazepines are on the FAA's Do Not Issue list. These medications are disqualifying due to their sedating effects and potential for dependence. A significant washout period is required after discontinuation.

What is the FAA status of Alprazolam?

Alprazolam has a status of "Disqualifying" under FAA medical certification policy. The certification pathway is: Do Not Issue (DNI) list.

Can I fly while taking Alprazolam?

Alprazolam is currently disqualifying for FAA medical certification. You cannot fly while taking this medication. A washout period and evaluation are typically required after discontinuation. Consult an AME or aviation attorney before making any medication changes.

Important Notice

The FAA does not publish a comprehensive list of “approved” medications. The information on this page represents our interpretation of publicly available FAA guidance and is provided for informational and educational purposes only. It does not constitute medical advice, legal advice, or a guarantee of certification outcome.

The primary issue with the FAA is always whether the underlying medical condition — not just the medication — is compatible with safe flight. You should only start, stop, or change medications after consulting your treating physician. Always consult with a qualified Aviation Medical Examiner (AME) for guidance specific to your situation. FAA policies are subject to change. ClearedMed is not affiliated with or endorsed by the FAA.